Human Excretory System
It includes kidneys, ureters, urinary bladder & urethra.

Structure of Kidney
- Reddish brown, bean-shaped structures situated between the levels of last thoracic & 3rd lumbar vertebra.
- Length: 10-12 cm, width: 5-7 cm, thickness: 2-3 cm. Average weight: 120-170 gm.
- It is enclosed in a tough, 3-layered fibrous renal capsule.
- On the concave side of kidney, there is an opening (hilum or hilus) through which blood vessels, nerves, lymphatic ducts and ureter enter the kidney.
- Hilum leads to funnel shaped cavity called renal pelvis with projections called calyces.
- A kidney has outer cortex & inner medulla.
- Medulla has few conical projections called medullary pyramids (renal pyramids) projecting into the calyces.
- Cortex extends in between the medullary pyramids as renal columns (Columns of Bertini).
- Each kidney has nearly one million tubular nephrons.

Nephron

- Nephrons are the structural & functional units of kidney.
- Each nephron has 2 parts: Glomerulus & Renal tubule.
- Glomerulus: A tuft of capillaries formed by afferent arteriole (a fine branch of renal artery). Blood from glomerulus is carried away by efferent arteriole.
- Renal tubule: It begins with a double walled cup-like Bowman’s capsule, which encloses the glomerulus.
- The tubule continues with proximal convoluted tubule (PCT), Henle’s loop & distal convoluted tubule (DCT).
- Henle’s loop is hairpin-shaped. It has descending and ascending limbs.
- The DCTs of many nephrons open into a collecting duct. Collecting duct extends from cortex to inner parts of medulla. They converge and open into the renal pelvis through medullary pyramids in the calyces. lip>Malpighian body (Renal corpuscle), PCT and DCT are situated in renal cortex. Loop of Henle dips into medulla.
- The efferent arteriole forms a fine capillary network (peritubular capillaries) around the renal tubule. A minute vessel of this network runs parallel to Henle’s loop forming a ‘U’ shaped vasa recta.
Glomerulus + Bowman’s capsule = Malpighian body
Types of nephrons
- Cortical nephrons (85%): In this, the Henle’s loop is short and extends only very little into the medulla. Vasa recta is absent or highly reduced.
- Juxtamedullary nephrons (15%): In this, Henle’s loop is long and runs deep into medulla. Vasa recta present.
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