Friday, April 19, 2013

List of Hormonal disorders



Disorders due to hormone deficiency (Hyposecretion)

Name of disorder
Hyposecretion of
Symptoms
1.       Acromicria (in adults)
Somatotrophin
Bones of the face and extremities are small and delicate.
2.       Addison’s disease
Aldosterone
Hypertension, dizziness, vomiting, diarrhea, low blood sugar, low plasma Na+, high plasma K+, increased urinary Na+ and bronze like pigmentation of skin.
3.       Cretinism (in children)
Thyroxin
Retarded growth, low intelligence, delayed sexual maturity.
4.       Diabetes insipidus
Vasopressin (ADH)
Enormous secretion of urine (polyuria), excess thirst (polydypsia) etc
5.       Diabetes mellitus
Insulin
Hyperglycemia (high sugar level in blood), glycosuria (sugar in urine), polyphagia (overeating), polydypsia (excess thirst) and polyuria (frequent urination).
6.       Dwarfism
Somatotrophin
Short in stature.
7.       Myxoedema (in adults)
Thyroxin
Physical sluggishness, mental dullness, low metabolic rate, dry and coarse skin and puffy face.
8.       Tetany
Parathormone (PTH)
Steep drop in blood calcium level, abnormal rise in excitability of nerves and muscles, sustained and violent contraction of muscles of face, larynx, hands and feet.
9.       Eunuchoidism
Testosterone
Lack male secondary sexual characters, sterility etc

Disorders due to excess hormone (Hypersecretion)

Name of disorder
Hypersecretion of
Symptoms
1.       Acromegaly (in adults)
Somatotrophin
Abnormal growth of bones of face, lower jaw, hands and feet. Enlargement of internal organs such as lungs, spleen etc
2.       Adrenal virilism (in female)
Sex corticoid
Masculanization of females such as growth of beards and moustaches and male voice etc.
3.       Conn’s syndrome
Aldosterone
Headache, Excessive urination at night, Excessive thirst, Excessive urination, Increased volume of blood, Increased blood sodium level, High alkalinity of blood and body fluids,
4.       Cushing’s syndrome
Cortisol
High blood sugar, obesity, deposition of fat in the face, neck etc. rise in plasma Na+ and high BP. In acute condition it leads to mental depression and impotency.
5.       Exophthalmic goiter (Grave’s disease)
Thyroxin
Hypertrophy of thyroid gland, increased metabolism, high rate of heartbeat, bulging eyeballs, restlessness, nervousness and loss of weight.
6.       Gigantism (in children)
Somatotrophin
Excessive height, extreme bone, muscle and organ growth.
7.       Hyperglycaemia
Glucagon
Polyphagia, Polydipsia, Polyuria, Blurred vision, Fatigue (sleepiness), Weight loss
Poor wound healing (cuts, scrapes, etc.), Dry mouth, Dry or itchy skin, Tingling in feet or heels, Erectile dysfunction, Recurrent infections, external ear infections (swimmer's ear), Cardiac arrhythmia, Stupor, Coma, Seizures
8.       Insulin shock
Insulin
Abnormal lowering of blood glucose (hypoglycemia), sudden fall of body temperature, fatigue, tremors and unconsciousness.
9.       Kidney stone
Parathormone
Accumulation of calcium in blood and it precipitate with phosphates to form kidney stones.
10.     Osteitis fibrosa cystica
Parathormone
Calcification of soft tissues like blood vessels



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