Fat Soluble Vitamins
Vitamins
|
Discovered by
|
Daily
requirement
|
Sources
|
Functions
|
Deficiency
|
Vitamin A (Retinol, carotenoid, anti- xerophthalmic vitamin,
vitamin of growth)
|
Mc
Collum & Davis (isolated by Holmus)
|
2 mg
|
Carrots, pumpkin, sweet potatoes, tomato, yellow coloured
fruits, pink grape fruits, apricots, leafy vegetables (Animals synthesize
this vitamin from carotene. So it is called Provitamin A.
Fish liver oil, butter, egg yolk, milk, cod liver oil, ghee
|
Synthesis of muco- polysaccharides so important for body
growth.
Maintain integrity and secretory activity of epithelial
glandular cells.
Night vision
|
Nyctalopia (Henerolopia)
Xerophthalmia
Dermatitis
Increased susceptibility to infection and cancer
Keratomalacia (Toad’s skin)
Stunted growth
Sterility
|
Vitamin D (Antirachitic vitamin, alciferol, sunshine vitamin
5 forms: D1, D2, D3, D4,
D5
|
Steenbock
& Hess
|
0.01
mg
|
Fish liver oil, butter, milk, egg, cheese, margarine, cream,
oysters & cereals.
Synthesized in skin from ergosterol (Provitamin D)
|
Ca/ P balance
Increase absorption of Ca from intestine.
|
Rickets (in children)
Osteomalacia (Especially
in pregnant woman)
|
Vitamin E (Tocopherol, antisterility vitamin, fertility
factor, beauty vitamin)
3 forms: α, β & γ
|
Evans &
Sore
|
15 mg
|
Wheat germ, corn, nuts, seeds, olives, spinach, asparagus,
leafy vegetables, vegetable oils, and their products, margarine, cotton seed
oils
|
Antioxidant and prevents oxidative destruction of other
vitamins (E.g. vit.K)
Prevents formation of unsaturated fatty acids so prevents
brown pigmentation
Normal working of gonads
Normal child birth
Removes wrinkles of skin, scars
|
Sterility
|
Vitamin K (Phylloquinone/ antihaemerrhagic vitamin)
3 forms:
K1 (phylloquinone) K2 (menaquinone) K3
(mandione)
|
Dam &
Droisy
|
0.07-0.14
mg
|
Cabbage, cauliflower, spinach, soyabeans, cereals, liver, egg
yolk.
K2 - by intestinal bacteria
K3 - synthetic form.
|
Formation of prothrombin from liver cells
Blood coagulation
Acts as coenzyme Q and participates in ETC.
|
Profuse bleeding
(Haemerrhage)
|