NEET Topic-wise & A
Topic 1: CELL CYCLE
NEET: Previous Years Questions
01: Following are the stages of cell division: (NEET 2024)
A. Gap 2 phase
B. Cytokinesis
C. Synthesis phase
D. Karyokinesis
E. Gap 1 phase
Choose the correct sequence of stages from the options given below:
(1) C-E-D-A-B
(2) E-B-D-A-C
(3) B-D-E-A-C
(4) E-C-A-D-B
✅ (4) E-C-A-D-B
02: Match List I with List II: (NEET 2023)
Choose the correct answer from the options given below:
(1) A-IV, B-II, C-I, D-III
(2) A-IV, B-I, C-II, D-III
(3) A-II, B-IV, C-I, D-III
(4) A-III, B-II, C-IV, D-I
✅ (2) A-IV, B-I, C-II, D-III
03: Given below are two statements: (NEET 2023)
Statement I: During G0 phase of cell cycle, the cell is metabolically inactive.
Statement II: The centrosome undergoes duplication during S phase of interphase.
In the light of the above statements, choose the most appropriate answer from the options given below:
(1) Both Statement I and Statement II are incorrect.
(2) Statement I is correct but Statement II is incorrect.
(3) Statement I is incorrect but Statement II is correct.
(4) Both Statement I and Statement II are correct.
✅ (3) Statement I is incorrect but Statement II is correct.
04: Among eukaryotes, replication of DNA takes place in: (NEET 2023)
(1) S phase
(2) G1 phase
(3) G2 phase
(4) M phase
✅ (1) S phase
05: Match List -I with List - II. (NEET 2021)
Choose the correct answer from the options given below.
(a) (b) (c) (d)
(1) (iii) (ii) (i) (iv)
(2) (iv) (ii) (iii) (i)
(3) (iv) (i) (ii) (iii)
(4) (ii) (iv) (iii) (i)
✅ (3) (iv) (i) (ii) (iii)
06: The centriole undergoes duplication during:
(1) S-phase
(2) Prophase
(3) Metaphase
(4) G2 phase (NEET 2021)
✅ (1) S-phase
07: Identify the correct statement with regard to G1 phase (Gap 1) of interphase. (NEET 2020)
(1) Cell is metabolically active, grows but does not replicate its DNA.
(2) Nuclear Division takes place.
(3) DNA synthesis or replication takes place.
(4) Reorganization of all cell components takes place.
✅ (1) Cell is metabolically active, grows but does not replicate its DNA.
08: Some dividing cells exit the cell cycle and enter vegetative inactive stage. This is called quiescent stage (G0). This process occurs at the end of:
(1) S phase
(2) G2 phase
(3) M phase
(4) G1 phase (NEET 2020)
✅ (4) G1 phase
09: The correct sequence of phases of cell cycle is:
(1) M → G1 → G2 → S
(2) G1 → G2 → S → M
(3) S → G1 → G2 → M
(4) G1 → S → G2 → M (NEET 2019)
✅ (4) G1 → S → G2 → M
10: Cells in G0 phase:
(1) exit the cell cycle
(2) enter the cell cycle
(3) suspend the cell cycle
(4) terminate the cell cycle (NEET 2019)
✅ (1) exit the cell cycle
11: During cell growth, DNA synthesis takes place on
(1) S-phase
(2) G1 -phase
(3) G2 -phase
(4) M phase (NEET-II 2016)
✅ (1) S-phase
12: When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?
(1) G1 /S
(2) G2 /M
(3) M
(4) Both G2 /M and M (NEET-II 2016)
✅ (2) G2 /M
Model Questions
13: The growth and reproduction of all organisms depend on
(1) The division of cells and tissues
(2) The division and enlargement of cells
(3) The division & enlargement of cells and tissues
(4) The enlargement of cells
✅ (2) The division and enlargement of cells
14: Duration of cell cycle in a typical eukaryotic cell such as human cell is about
(1) 24 minutes
(2) 90 minutes
(3) 24 hours
(4) 90 hrs
✅ (3) 24 hours
15: The two basic phases of cell cycle are
(1) Mitosis & meiosis
(2) Mitosis & Interkinesis
(3) Interphase & M phase
(4) G1 and G2 phase
✅ (3) Interphase & M phase
16: The phase between two successive M phases is called
(1) G1 phase
(2) Antephase
(3) Karyokinesis
(4) Interphase
✅ (4) Interphase
17: Three phases involved in interphase are
(1) G1 phase, G2 phase, M phase
(2) G1 phase, karyokinesis, cytokinesis
(3) G1 phase, S phase, G2 phase
(4) G1 phase, S phase, M phase
✅ (3) G1 phase, S phase, G2 phase
18: Select the false statement.
(1) Interphase lasts more than 95% of the duration of cell cycle
(2) Interphase includes cell division & DNA synthesis
(3) S phase is the second phase of interphase and is the longest phase
(4) In both G1 & G2 phases, synthesis of RNA and proteins occurs
✅ (2) Interphase includes cell division & DNA synthesis
19: Which is correctly labelled?
(1) A= G1 phase B= S phase C= G0 phase D= G2 phase E= M phase
(2) A= G0 phase B= S phase C= G1 phase D= G2 phase E= M phase
(3) A= M phase B= G0 phase C= G1 phase D= S phase E= G2 phase
(4) A= G0 phase B= G1 phase C= S phase D= G2 phase E= M phase
✅ (4) A= G0 phase B= G1 phase C= S phase D= G2 phase E= M phase
20: Which of the following represents actual cell division?
(1) G1 phase
(2) S phase
(3) G2 phase
(4) M phase
✅ (4) M phase
21: The cells that do not divide further exit G1 phase and enter an inactive stage called
(1) Quiescent (G0) stage
(2) G2 phase
(3) Synthetic (S) phase
(4) Early prophase
✅ (1) Quiescent (G0) stage
22: The cells that do not show division are
(1) Epithelial cells, heart cells and megakaryocytes
(2) Neurons, skeletal and cardiac muscle cells
(3) Neurons, bone marrow cells and muscle cells
(4) Hemocytoblasts, heart cells and epithelial cells
✅ (2) Neurons, skeletal and cardiac muscle cells
Topic 2: MITOSIS
NEET: Previous Years Questions
23: Spindle fibers attach to kinetochores of chromosomes during (NEET 2024)
(1) Prophase
(2) Metaphase
(3) Anaphase
(4) Telophase
✅ (2) Metaphase
24: The fruit fly has 8 chromosomes (2n) in each cell. During interphase of Mitosis if the number of chromosomes at G1 phase is 8, what would be the number of chromosomes after S phase? (NEET 2021)
(1) 8
(2) 16
(3) 4
(4) 32
✅ (1) 8
25: Which of the following options gives the correct sequence of events during mitosis? (NEET 2017)
(1) Condensation → Nuclear membrane disassembly → Arrangement at equator → Centromere division → Segregation → Telophase
(2) Condensation → Crossing over → Nuclear membrane disassembly → Segregation → Telophase
(3) Condensation → Arrangement at equator → Centromere division → Segregation → Telophase
(4) Condensation → Nuclear membrane disassembly → Crossing over → Segregation → Telophase
✅ (1) Condensation → Nuclear membrane disassembly → Arrangement at equator → Centromere division → Segregation → Telophase
26: Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cell. If APC is defective in a human cell, which of the following is expected to occur? (NEET 2017)
(1) Chromosomes will be fragmented.
(2) Chromosomes will not segregate.
(3) Recombination of chromosome arms will occur.
(4) Chromosomes will not condense.
✅ (2) Chromosomes will not segregate.
27: Spindle fibres attach on to (NEET-I 2016)
(1) centromere of the chromosome
(2) kinetosome of the chromosome
(3) telomere of the chromosome
(4) kinetochore of the chromosome
✅ (4) kinetochore of the chromosome.
28: Which of the following is not a characteristic feature during mitosis in somatic cells? (NEET-I 2016)
(1) Chromosome movement
(2) Synapsis
(3) Spindle fibres
(4) Disappearance of nucleolus
✅ (2) Synapsis
Model Questions
29: Given below are some statements regarding mitosis Select the wrong one.
(1) It is the cell division occurring in somatic cells.
(2) It is also called as equational division as the number of chromosomes in the parent and progeny cells is same.
(3) It occurs only in diploid cells.
(4) It helps to retain the same chromosome number in all somatic cells.
✅ (3) It occurs only in diploid cells.
30: The correct sequence of stages in karyokinesis is
(1) Metaphase, Prophase, Telophase & Anaphase
(2) Prophase, Metaphase, Anaphase & Telophase
(3) Telophase, Prophase, Anaphase & Metaphase
(4) Anaphase, Prophase, Telophase & Metaphase
✅ (2) Prophase, Metaphase, Anaphase & Telophase
31: The longest and shortest phases in mitosis is
(1) Prophase and Anaphase respectively
(2) Metaphase and Telophase respectively
(3) Anaphase and Prophase respectively
(4) Telophase and Metaphase respectively
✅ (1) Prophase and Anaphase respectively
32: In animal cells, during S phase, DNA replication begins in the ------ and the centriole duplication in the ------
(1) Nucleus, cytoplasm
(2) Nucleus, nucleus
(3) Cytoplasm, nucleus
(4) Cytoplasm, cytoplasm
✅ (1) Nucleus, cytoplasm
33: Match the following:
A B C D
(1) 2 3 4 1
(2) 4 3 2 1
(3) 3 4 1 2
(4) 3 1 4 2
✅ (4) 3 1 4 2
34: Which of the following does not occur during late prophase?
(1) Each chromosome splits into two chromatids attached together at the centromere
(2) The nuclear envelope, nucleolus, Golgi complexes & endoplasmic reticulum disappear
(3) Chromosomes form two sister chromatids
(4) Condensation of chromosomes continues
✅ (3) Chromosomes form two sister chromatids
35: In animal cells, during late prophase, the centrioles
(1) Move to opposite poles and radiate out astral rays
(2) Move to equator and radiate out astral rays
(3) Move to equator and radiate out spindle fibres
(4) Move to opposite poles and start uncoiling of chromosomes
✅ (1) Move to opposite poles and radiate out astral rays
36: Regarding prophase
1. Prophase is the first stage of mitosis
2. Prophase follows S and G2 phases of interphase
3. Prophase is marked by the initiation of condensation of chromosomal material.
4. The centriole which had undergone duplication during S phase of interphase, now begins to move towards opposite poles of the cell
(1) All are correct statements
(2) Only 1,3 are correct statements
(3) Only 2,4 are correct statements
(4) Only 1,2,3 are correct statements
✅ (1) All are correct statements
37: The spindle fibres disappear during
(1) Prophase
(2) Metaphase
(3) Anaphase
(4) Telophase
✅ (4) Telophase
38: The figure given below represents
(1) Transition to late Prophase
(2) Transition to Metaphase
(3) Transition to Anaphase
(4) Transition to Telophase
✅ (2) Transition to Metaphase
39: Which of the following options gives the correct sequences of events during mitosis?
(1) Condensation → nuclear membrane disassembly → crossing over → segregation → telophase
(2) Condensation → nuclear membrane disassembly → arrangement at equator → centromere division → segregation → telophase
(3) Condensation → crossing over → nuclear membrane disassembly → segregation → telophase
(4) Condensation → arrangement at equator → centromere division → segregation → telophase
✅ (2) Condensation → nuclear membrane disassembly → arrangement at equator → centromere division → segregation → telophase
40: Which of the following is not the significance of mitosis?
(1) It produces diploid daughter cells with identical genome
(2) It helps to retain the same chromosome number in all somatic cells
(3) It restores the nucleo-cytoplasmic ratio that disturbed due to cell growth
(4) It causes genetic variation due to crossing over in the population of organisms
✅ (4) It causes genetic variation due to crossing over in the population of organisms
41: Cytokinesis in plant cell is different from animal cell due to the presence of
(1) Large vacuole
(2) Cell wall
(3) Chloroplasts
(4) All of these
✅ (2) Cell wall
42: Which is not occurring in cytokinesis of plants?
(1) The vesicles formed from Golgi bodies accumulate at the equator
(2) Cell plate is formed
(3) A cleavage furrow is appeared in the plasma membrane
(4) The cell plate becomes the middle lamella
✅ (3) A cleavage furrow is appeared in the plasma membrane
Topic 3: MEIOSIS
NEET: Previous Years Questions
43: Match List I with List II. (NEET 2024)
Choose the correct answer from the options given below
(1) A-IV, B-II, C-III, D-I
(2) A-I, B-II, C-IV, D-III
(3) A-II, B-IV, C-I, D-III
(4) A-IV, B-III, C-II, D-I
✅ (3) A-II, B-IV, C-I, D-III
44: Given below are two statements: (NEET 2024)
Statement I: Chromosomes become gradually visible under light microscope during leptotene stage.
Statement II: The beginning of diplotene stage is recognized by dissolution of synaptonemal complex.
In the light of the above statements, choose the correct answer from the options given below:
(1) Both Statement I and Statement II are true
(2) Both Statement I and Statement II are false
(3) Statement I is true but Statement II is false
(4) Statement I is false but Statement II is true
✅ (1) Both Statement I and Statement II are true
45: The process of appearance of recombination nodules occurs at which sub stage of prophase I in meiosis?
(1) Pachytene
(2) Diplotene
(3) Diakinesis
(4) Zygotene (NEET 2023)
✅ (1) Pachytene
46: Select the correct statements.
A. Tetrad formation is seen during Leptotene.
B. During Anaphase, the centromeres split and chromatids separate.
C. Terminalization takes place during Pachytene.
D. Nucleolus, Golgi complex and ER are reformed during Telophase.
E. Crossing over takes place between sister chromatids of homologous chromosome.
Choose the correct answer from the options given below:
(1) B and D only
(2) A, C and E only
(3) B and E only
(4) A and C only (NEET 2023)
✅ (1) B and D only
47: Which of the following stages of meiosis involves division of centromere? (NEET 2023)
(1) Metaphase II
(2) Anaphase II
(3) Telophase
(4) Metaphase I
✅ (2) Anaphase II
48: Match the following with respect to meiosis:
Select the correct option from the following:
(a) (b) (c) (d)
(1) (i) (ii) (iv) (iii)
(2) (ii) (iv) (iii) (i)
(3) (iii) (iv) (i) (ii)
(4) (iv) (iii) (ii) (i) (NEET 2020)
✅ (4) (iv) (iii) (ii) (i)
49: Which stage of meiotic prophase shows terminalisation of chiasmata as its distinctive feature? (NEET 2021)
(1) Leptotene
(2) Zygotene
(3) Diakinesis
(4) Pachytene
✅ (3) Diakinesis
50: Which of the following stages of meiosis involves division of centromere? (NEET 2021)
(1) Metaphase I
(2) Metaphase II
(3) Anaphase II
(4) Telophase II
✅ (3) Anaphase II
51: Dissolution of the synaptonemal complex occurs during: (NEET 2020)
(1) Diplotene
(2) Leptotene
(3) Pachytene
(4) Zygotene
✅ (1) Diplotene
52: The stage during which separation of the paired homologous chromosomes begins is (NEET 2018)
(1) Pachytene
(2) Diplotene
(3) Diakinesis
(4) Zygotene
✅ (2) Diplotene
53: Match the stages of meiosis in column I to their characteristic features in column II and select the correct option using the codes given below. (NEET-II 2016)
(1) A-(iii), B-(iv), C-(ii), D-(i)
(2) A-(i), B-(iv), C-(ii), D-(iii)
(3) A-(ii), B-(iv), C-(iii), D-(i)
(4) A-(iv), B-(iii), C-(ii), D-(i)
✅ (1) A-(iii), B-(iv), C-(ii), D-(i)
54: In meiosis crossing over is initiated at
(1) zygotene
(2) diplotene
(3) pachytene
(4) leptotene (NEET-I 2016)
✅ (3) pachytene
Model Questions
55: Meiosis occurs during
(1) Gametogenesis
(2) Body growth
(3) Tissue repair
(4) Crossing over
✅ (1) Gametogenesis
56: Which of the following is not the key feature of meiosis?
(1) It involves pairing of homologous chromosomes and recombination between them.
(2) It involves two cycles of DNA replication and cell division.
(3) Meiosis I begins after replication of parental chromosomes to form identical sister chromatids at the S phase.
(4) Four haploid cells are formed at the end of meiosis II.
✅ (2) It involves two cycles of DNA replication and cell division.
57: Choose the correct sequence of events of Prophase I?
(1) Zygotene, Leptotene, Diplotene, Pachytene & Diakinesis
(2) Pachytene, Diplotene, Leptotene, Zygotene & Diakinesis
(3) Diplotene, Leptotene, Zygotene, Pachytene & Diakinesis
(4) Leptotene, Zygotene, Pachytene, Diplotene & Diakinesis
✅ (4) Leptotene, Zygotene, Pachytene, Diplotene & Diakinesis
58: Match the following:
A B C D E
(1) 2 3 5 1 4
(2) 4 3 2 5 1
(3) 5 4 1 2 3
(4) 3 1 4 5 2
✅ (2) 4 3 2 5 1
59: During zygotene, similar chromosomes start pairing together. It is called
(1) Crossing over
(2) Recombination
(3) Synapsis
(4) Diakinesis
✅ (3) Synapsis
60: Each pair of homologous chromosomes is called a
(1) Bivalent
(2) Tetrad
(3) Chiasmata
(4) Diad
✅ (1) Bivalent
61: Crossing over is
(1) The pairing of homologous chromosomes with the help of a complex structure called synaptonemal complex.
(2) The exchange of genetic material between sister chromatids of a chromosomes in presence of recombinase.
(3) The pairing of non-homologous chromosomes with the help of a complex structure called synaptonemal complex.
(4) The exchange of genetic material between non-sister chromatids of two homologous chromosomes in presence of recombinase.
✅ (4) The exchange of genetic material between non-sister chromatids of two homologous chromosomes in presence of recombinase.
62: Kinetochore is located in
(1) Centriole
(2) Centromere
(3) Chromatids
(4) Lysosome
✅ (2) Centromere
63: Recombination is completed by the end of
(1) Zygotene
(2) Pachytene
(3) Diplotene
(4) Diakinesis
✅ (2) Pachytene
64: This short stage between the two meiotic divisions is called
(1) Interphase
(2) Antephase
(3) Interkinesis
(4) Cytokinesis
✅ (3) Interkinesis
65: “Thin threaded” stage refers to
(1) Leptotene
(2) Zygotene
(3) Pachytene
(4) Diplotene
✅ (1) Leptotene
66: Number of chromatids at metaphase is
(1) Two each in mitosis and meiosis
(2) Two in mitosis and one in meiosis
(3) Two in mitosis and four in meiosis
(4) One in mitosis and two in meiosis
✅ (1) Two each in mitosis and meiosis
67: Total number of reproductive cells required for the formation of 128 gametes in man is
(1) 32
(2) 64
(3) 16
(4) 128
✅ (1) 32